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2023

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A prefilled syringe filling machine is a device used to manufacture medical devices

A pre-filled syringe filling machine is a device used to manufacture medical equipment. It is mainly used to inject liquid medicine into small syringes so that patients can inject easily. It usually consists of a production line and several workstations. Workstation 1, cleans and loads the needle and plastic syringe; Workstation 2, accurately fills the specified amount of liquid medicine into the syringe, and uses a vacuum barrel to expel air bubbles; Workstation 3, connects the needle to the filled syringe; Workstation 4 packs and checks the filled syringes. The whole process is controlled by computer and completed automatically under the whole monitoring.


A pre-filled syringe filling machine is a device used to manufacture medical equipment. It is mainly used to inject liquid medicine into small syringes so that patients can inject easily. It usually consists of a production line and several workstations. Workstation 1, cleans and loads the needle and plastic syringe; Workstation 2, accurately fills the specified amount of liquid medicine into the syringe, and uses a vacuum barrel to expel air bubbles; Workstation 3, connects the needle to the filled syringe; Workstation 4 packs and checks the filled syringes. The whole process is controlled by computer and completed automatically under the whole monitoring.

The advantage of the prefilled syringe filling machine is that it is relatively simple and easy to operate, can accurately control the amount of drug delivery, and has high production efficiency, which can meet the needs of large-scale production. In addition, it can significantly reduce the risk of human error and improve work efficiency and production speed. Protect production staff and patients from the risk of cross-infection. However, it is important to note that the instrument must be rigorously certified and validated. And QC inspection is carried out on a regular basis to ensure that there are no problems. If the operation is not done properly or there is a problem with the equipment, it may cause the liquid medicine to soak into the needle tip and the shell to rise to serious pollution, which will bring huge health risks to patients and even loss of life. Therefore, before using a prefilled syringe filling machine, it is also necessary to ensure that its operators have received relevant training and have an adequate level of skill and knowledge to operate it safely and effectively. At the same time, manufacturers also need to comply with various relevant laws and regulations.

Simple steps to use the prefilled syringe filling machine:
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1. Preparations
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1.1 Identify the required prefilled syringe sizes (usually 1ml, 2ml, and 5ml) and install the correct syringe "rack" or clamp as needed.
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1.2 Select the appropriate delivery pipeline and pump according to the characteristics of the filled medicine.
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2. Liquid medicine filling
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2.1 Pour the herbal solution into the raw material tank.
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2.2 Adjust the volume to be filled on the syringe rack, and place the glass slide on the table, making sure that the filling port is upward.
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2.3 Use the hand wheel system to adjust the drug flow, and start the syringe according to the instructions on the operation panel.
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3. Pre-filled rubber stopper
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3.1 Check to see if any air bubbles remain in the syringe after filling.
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3.2 Keep the rubber stopper of the syringe steady and still before priming the drug product into it.
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3.3 Let the syringe stand for a while to allow the foam to disappear and to ensure that the liquid level is stable.
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4. Sealed packaging
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4.1 Remove the wire on the rubber plug and leave the machine.
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4.2 Place the rubber pad on the operating table, put the filling port of the syringe into the upper mold, close the mold cover, and enter the sealing instruction.
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4.3 After waiting for a period of time, remove the sealing mold and take out the sealed syringe.
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It should be noted that when using the prefilled syringe filling machine, be sure to keep the equipment clean. Equipment should be cleaned and maintained at the end of each use.

Keyword:

A pre-filled syringe filling machine